Rheumatoid Arthritis Essay -- essays research papers

Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the sums and connective create from raw stuff. The result is red that produces permanent dam days in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by wear and tear of the joints. In telephone circuit to (OA), derelict arthritis is characterized by inflammation mostly of the joints, hardly is a usual personate disease. The type of joint that is chronically affected is the synovial joint. The clappers that are at a synovial joint are cover by articular cartilage which reduces friction and absorbs shock. The space between the articulating swot up is called the synovial cavity, which is surrounded by an articular capsulate. The outer mould of the capsule is called the fibrous capsule and consists of dense irregular connective tissue. The inner layer of the capsule is lin ed with the synovial membrane, which is composed of areolar connective tissue with elastic fibers and whitethorn also contain adipose tissue. In a healthy joint the synovial membrane produces synovial fluid. The fluid non only reduces friction and lubricates the joint, but it also supplies nutrients and removes debris, wastes, and microbes.Rheumatoid arthritis affects twice as many women as it does men. It tail develop in child hood, but in most cases it develops between the ages of twenty-five and fifty. Rheumatoid arthritis itself may not be inherited, but what potful be inherited are the constituents that may make someone more alikely to develop the disease including those genes that get over the immune schema.Normally the immune system protects your body against foreign proteins like bacteria, fungi, or viruses and it does this by attacking them and producing antibodies. In Rheumatoid arthritis the immune system loses its ability to tell the difference between these antig ens and the bodies normal cells. The body begins to attack the normal cells by using its plasma cells to produce antibodies called blood serum rheumatoid factors (RF). The chemical messengers called cytokines control the inflammatory process. One of the key cytokines is called neoplasm Necrosis Factor or TNF which is part of the normal inflammatory process. People with rheumatoid arthritis have been foun... ...neumonitis, bone marrow suppression, and with long verge use even malignancy. Treatment also consists of rest and a nutritious diet. Some supplements such as fish or plant oils can be taken to partially relief some of Cavezza 7the symptoms because they can decrease the production of prostaglandins. Exercise and physiotherapy can restore muscularity mass and help preserve the range of motion. This is recommended after the inflammation subsides. some other alternative if or when drugs fail is arthroscopic or surgical synovectomy, which temporarily relieves inflammation. p rosthetic replacement of joints is possible, but this greatly reduces the functionality. Rheumatoid arthritis affects everyone differently. In most patients, joint symptoms develop gradually over several years. In some people, rheumatoid arthritis may progress rapidly. Other people may have rheumatoid arthritis for a limited period of time and then enter a period of remission. More than two million people in the join States alone have rheumatoid arthritis and with research and development of new drugs and gene therapy there may be a clearer picture of a patients coming(prenominal) and quality of life.